醇与烯醇醚的交换反应
实例一
To a 0.1 M solution of 1-phenylbut-2-yn-1-ol (1 mmol) in ethylvinyl ether was added to
0.6 mmol of mercuric acetate. The reaction mixture was refluxed at 45 °C for 12 hours before quenching with a saturated aqueous sodium carbonate solution. The organic phase was extracted using diethyl ether and dried over anhydrous potassium carbonate. The solvent was removed under vacuum and the crude vinyl ether was purified on alumina gel column using hexane as aneluent. Vinyl ether was obtained in 60% yield (0.1g).
醇与烯醇醚的交换反应
实例一
To a 0.1 M solution of 1-phenylbut-2-yn-1-ol (1 mmol) in ethylvinyl ether was added to
0.6 mmol of mercuric acetate. The reaction mixture was refluxed at 45 °C for 12 hours before quenching with a saturated aqueous sodium carbonate solution. The organic phase was extracted using diethyl ether and dried over anhydrous potassium carbonate. The solvent was removed under vacuum and the crude vinyl ether was purified on alumina gel column using hexane as aneluent. Vinyl ether was obtained in 60% yield (0.1g).
Reference: Org.Lett. 2013, 15, 4662-4665.
百度翻译：向1-苯基-2-乙烯基-1-醇（1 mmol）的0.1 M溶液中添加
0.6 mmol醋酸汞。反应混合物在45℃回流12小时，然后用饱和碳酸钠水溶液淬火。有机相用乙醚萃取并在无水碳酸钾上干燥。溶剂在真空下除去，粗乙烯基醚在氧化铝凝胶柱上以正己烷为溶剂进行纯化。乙烯基醚的收率为60%（0.1g）。
览博网
